Phylogenetics of Transporter Family


Protein sequence in FASTA format
Multiple sequence alignment (View it with JalView)
TreeView Document (View it with TreeView)
Phylogenetic tree (Phylogram) (View it with ATV)

ATP-Dependent

ABC: The ATP-binding Cassette (ABC) Superfamily



ArsAB: The Arsenite-Antimonite (ArsAB) Efflux Family



CEPT: The Chloroplast Envelope Protein Translocase (CEPT or Tic-Toc) Family



F-ATPase: The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily



H+-PPase: The H+-translocating Pyrophosphatase (H+-PPase) Family



IISP: The Type II (General) Secretory Pathway (IISP) Family



MPT: The Mitochondrial Protein Translocase (MPT) Family



P-ATPase: The P-type ATPase (P-ATPase) Superfamily



S-DNA-T: The Septal DNA Translocator (S-DNA-T) Family


Ion Channels

ACC: The ATP-gated Cation Channel (ACC) Family



Amt: The Ammonia Transporter Channel (Amt) Family



Annexin: The Annexin (Annexin) Family



Bcl-2: The Bcl-2 (Bcl-2) Family



Bestrophin: The Anion Channel-forming Bestrophin (Bestrophin) Family



BNip3: The BCL2/Adenovirus E1B-interacting Protein 3 (BNip3) Family



CD20: The CD20 Ca2+ Channel (CD20) Family



CLIC: The Intracellular Chloride Channel (CLIC) Family



Connexin: The Gap Junction-forming Connexin (Connexin) Family



CRAC-C: The Ca2+ Release-activated Ca2+ (CRAC) Channel (CRAC-C) Family



Ctr: The Copper Transporter (Ctr) Family



E-ClC: The Epithelial Chloride Channel (E-ClC) Family



ENaC: The Epithelial Na+ Channel (ENaC) Family



GIC: The Glutamate-gated Ion Channel (GIC) Family of Neurotransmitter Receptors



Hsp70: The Cation Channel-forming Heat Shock Protein-70 (Hsp70) Family



ICC: The Intracellular Chloride Channel (ICC) Family



ICln: The Nucleotide-sensitive Anion-selective Channel, ICln (ICln) Family



Innexin: The Gap Junction-forming Innexin (Innexin) Family



IRK-C: The Inward Rectifier K+ Channel (IRK-C) Family



LIC: The Neurotransmitter Receptor, Cys loop, Ligand-gated Ion Channel (LIC) Family



Mid1: The Yeast Stretch-Activated, Cation-Selective, Ca2+ Channel, Mid1 (Mid1) Family



MIP: The Major Intrinsic Protein (MIP) Family



MIT: The CorA Metal Ion Transporter (MIT) Family



MscL: The Large Conductance Mechanosensitive Ion Channel (MscL) Family



MscS: The Small Conductance Mechanosensitive Ion Channel (MscS) Family



NSCC2: The Non-selective Cation Channel-2 (NSCC2) Family



PCC: The Polycystin Cation Channel (PCC) Family



Plasmolipin: The Plasmolipin (Plasmolipin) Family



PLB: The Phospholamban (Ca2+-channel and Ca2+-ATPase Regulator) (PLB) Family



PLM: The Phospholemman (PLM) Family



Presenilin: The Presenilin ER Ca2+ Leak Channel (Presenilin) Family



RIR-CaC: The Ryanodine-Inositol 1,4,5-triphosphate Receptor Ca2+ Channel (RIR-CaC) Family



Tic110: The Chloroplast Envelope Anion Channel-forming Tic110 (Tic110) Family



TRIC: The Homotrimeric Cation Channel (TRIC) Family



TRP-CC: The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family



Tweety: The Anion Channel Tweety (Tweety) Family



UAC: The Urea/Amide Channel (UAC) Family



UT: The Urea Transporter (UT) Family



VIC: The Voltage-gated Ion Channel (VIC) Superfamily


Outer Membrane Porins

FadL: The FadL Outer Membrane Protein (FadL) Family



MPP: The Mitochondrial and Plastid Porin (MPP) Family



OMA: The Outer Membrane Auxiliary (OMA) Protein Family



OmpIP: The Outer Membrane Protein Insertion Porin (OmpIP) Family



OMR: The Outer Membrane Receptor (OMR) Family



OOP: The OmpA-OmpF Porin (OOP) Family


Phosphotransferase System (PTS)

GPTS: General PTS



SSPTS: Sugar Specific PTS


Secondary Transporter

2-HCT: The 2-Hydroxycarboxylate Transporter (2-HCT) Family



AAA: The ATP:ADP Antiporter (AAA) Family



AAAP: The Amino Acid/Auxin Permease (AAAP) Family



AAE: The Aspartate:Alanine Exchanger (AAE) Family



AbgT: The p-Aminobenzoyl-glutamate Transporter (AbgT) Family



ACR3: The Arsenical Resistance-3 (ACR3) Family



AE: The Anion Exchanger (AE) Family



AEC: The Auxin Efflux Carrier (AEC) Family



AGCS: The Alanine or Glycine:Cation Symporter (AGCS) Family



AI-2E: The Autoinducer-2 Exporter (AI-2E) Family (Formerly the PerM Family, TC #9.B.22)



APC: The Amino Acid-Polyamine-Organocation (APC) Family



ArAE: The Aromatic Acid Exporter (ArAE) Family



ArsB: The Arsenite-Antimonite (ArsB) Efflux Family



AtoE: The Short Chain Fatty Acid Uptake (AtoE) Family



BASS: The Bile Acid:Na+ Symporter (BASS) Family



BCCT: The Betaine/Carnitine/Choline Transporter (BCCT) Family



BenE: The Benzoate:H+ Symporter (BenE) Family