| Confidence Level of Functional Assignments: | |||||||||
 |
Weak Bioinformatic Evidence |  |
Strong Bioinformatic Evidence |  |
Clear Orthologue to Experimentally Characterized |  |
Experimental Characterized | ||
|
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| The Auxin Efflux Carrier (AEC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
PSPTO4479  9 | malonate | ||||
| The Alanine or Glycine:Cation Symporter (AGCS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5500 10 | sodium ion/alanine | ||||
| The Amino Acid-Polyamine-Organocation (APC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5276 13 | proline | ||||
| PSPTO5356 (gabP) 12 | gamma-aminobutyrate | ||||
| PSPTO2026 12 | ethanolamin | ||||
| PSPTO1817 12 | aromatic amino acid | ||||
| The Aromatic Acid Exporter (ArAE) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0520 6 | fusaric acid? | ||||
| PSPTO1218 10 | fusaric acid? | ||||
| PSPTO3618 8 | fusaric acid? | ||||
| The Arsenite-Antimonite (ArsB) Efflux Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3798 (arsB) 11 | arsenite | ||||
| The Bile Acid:Na+ Symporter (BASS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3898 8 | sodium ion/bile acid | ||||
| The Betaine/Carnitine/Choline Transporter (BCCT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5269 12 | choline | ||||
| The Benzoate:H+ Symporter (BenE) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO2031 3 | benzoate | ||||
| The Ca2+:Cation Antiporter (CaCA) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0764 9 | calcium ion/proton | ||||
| PSPTO4477 11 | sodium/calcium ion | ||||
| The Cation Diffusion Facilitator (CDF) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4790 6 | cation efflux | ||||
| The Citrate-Mg2+:H+ (CitM) Citrate-Ca2+:H+ (CitH) Symporter (CitMHS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0062 12 | Mg++/citrate | ||||
| The Chloride Carrier/Channel (ClC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4619 9 | chloride channel | ||||
| The Monovalent Cation:Proton Antiporter-1 (CPA1) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0366 12 | sodium ion/proton | ||||
| PSPTO2517 10 | sodium ion/proton | ||||
| PSPTO5023 12 | sodium ion/proton | ||||
| The Monovalent Cation:Proton Antiporter-2 (CPA2) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4259 (kefC) 12 | potassium ion efflux | ||||
| PSPTO2355 12 | potassium ion efflux | ||||
| PSPTO5519 15 | sodium ion/proton | ||||
| The Monovalent Cation (K+ or Na+):Proton Antiporter-3 (CPA3) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3472 3 PSPTO3473 13PSPTO3474 2PSPTO3475 3PSPTO3476 3 | potassium ion/proton | ||||
| The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0233 (gltP) 8 | proton/glutamate | ||||
| PSPTO1682 (dctA-1) 8 PSPTO4063 (dctA-2) 8 | C4-dicarboxylate | ||||
| The Drug/Metabolite Transporter (DMT) Superfamily | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0210 ? 10 | ? | ||||
| PSPTO2344 ? 10 | ? | ||||
| PSPTO4083 10 | MadN homolog | ||||
| PSPTO1214 ? 10 | amino acid metabolite? | ||||
| PSPTO4901 ? 10 | ? | ||||
| PSPTO4979 3 | quaternary ammonium compound | ||||
| PSPTO0483 (rarD-1) 10 PSPTO3591 (rarD-2) 8 | chloramphenicol | ||||
| PSPTO3470 8 | drug/metabolite | ||||
| PSPTO1729 10 | amino acid metabolite? | ||||
| PSPTO3679 10 | amino acid metabolite? | ||||
| PSPTO3066 4 | drug/metabolite? | ||||
| The Formate-Nitrite Transporter (FNT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3296 6 | formate/nitrite | ||||
| The Gluconate:H+ Symporter (GntP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3565 12 | gluconate | ||||
| PSPTO5063 11 | gluconate | ||||
| PSPTO5115 12 | gluconate | ||||
| PSPTO1347 11 | gluconate | ||||
| The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO1760 11 | serine | ||||
| The K+ Uptake Permease (KUP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3993 (kup) 12 | potassium ion uptake | ||||
| The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO2206 (brnQ) 12 | branched-chain amino acid | ||||
| The L-Lysine Exporter (LysE) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4362 6 | L-lysine | ||||
| The Major Facilitator Superfamily (MFS) | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4306 (pcaT) 12 | dicarboxylic acid | ||||
| PSPTO4300 14 | multidrug efflux | ||||
| PSPTO4296 11 | dicarboxylic acid/alpha-ketoglutarate | ||||
| PSPTO4278 12 | chloramphenicol | ||||
| PSPTO2304 12 | nitrate | ||||
| PSPTO2340 (pcaK) 12 | 4-hydroxybenzoate | ||||
| PSPTO4383 14 | AmpG homolog | ||||
| PSPTO4357 12 | chloramphenicol/multidrug efflux | ||||
| PSPTO4202 12 | sugar/4-hydroxybenzoate | ||||
| PSPTO0407 14 | multidrug efflux | ||||
| PSPTO4105 10 | hexuronate | ||||
| PSPTO0999 12 | sugar | ||||
| PSPTO1718 12 | oxalate/formate | ||||
| PSPTO1617 11 | drug/sugar | ||||
| PSPTO1469 11 | metabolite | ||||
| PSPTO1363 12 | sugar/metabolite | ||||
| PSPTO1339 ? 10 | ? | ||||
| PSPTO1260 12 | cyanate | ||||
| PSPTO5219 11 | hexuronate | ||||
| PSPTO5238 (glpT) 12 | glycerol-3-phosphate | ||||
| PSPTO2467 10 | sugar/drug | ||||
| PSPTO3336 12 | citrate | 2.A.1.6.1 | |||
| PSPTO3304 12 | antibiotics | ||||
| PSPTO2496 12 | metabolite | ||||
| PSPTO2500 12 | sugar | ||||
| PSPTO2601 12 | AmpG homolog | ||||
| PSPTO2764 12 | antibiotic efflux | ||||
| PSPTO0094 12 | multidrug efflux | ||||
| PSPTO4774 12 | multidrug efflux | ||||
| PSPTO5112 12 | multidrug efflux? | ||||
| PSPTO4522 ? 12 | multidrug efflux | ||||
| PSPTO4548 11 | D-glucarate | ||||
| PSPTO4656 9 | multidrug efflux | ||||
| PSPTO2926 14 | multidrug efflux | ||||
| PSPTO3052 10 | sugar/drug | ||||
| PSPTO3686 12 | sugar/drug | ||||
| PSPTO3747 14 | multidrug efflux | ||||
| PSPTO3771 12 | tartrate/phthalate | ||||
| PSPTO3799 (fsr) 12 | fosmidomycin | ||||
| PSPTO0655 12 | multidrug efflux | ||||
| PSPTO0753 12 | multidrug efflux | ||||
| PSPTO0838 ? 12 | drug/sugar | ||||
| PSPTO2180 10 | D-galactonate | ||||
| PSPTO2104 12 | citrate | ||||
| PSPTO2103 12 | sugar/drug | ||||
| PSPTO2044 12 | 3-phenylpropionate? | ||||
| PSPTO1922 12 | multidrug efflux? | ||||
| PSPTO1917 12 | multidrug efflux | ||||
| PSPTO1906 12 | 4-hydroxyphenylacetate | ||||
| PSPTO1819 12 | multidrug efflux | ||||
| PSPTO3159 11 | multidrug efflux | ||||
| PSPTO5488 12 | proline/betaine | ||||
| PSPTO1612 12 | proline/betaine | ||||
| PSPTO1579 ? 12 | drug/sugar | ||||
| PSPTO3284 12 | phthalate/tartrate | ||||
| PSPTO3589 12 | multidrug efflux | ||||
| PSPTO3704 14 | multidrug efflux | ||||
| PSPTO3197 14 | multidrug efflux? | ||||
| PSPTO5340 13 | oxalate/formate | ||||
| PSPTO0871 11 | macrolide | ||||
| PSPTO0202 ? 12 | multidrug efflux | ||||
| PSPTO2345 9 | hexuronate | ||||
| PSPTO2688 12 | chloramphenicol | ||||
| PSPTO2802 (proP) 11 | citrate/proline/betaine | ||||
| PSPTO3801 12 | proline/betaine | ||||
| PSPTO3068 11 | sugar/drug | ||||
| PSPTO2947 12 | 4-hydroxybenzoate | ||||
| PSPTO2910 12 | tartrate/phthalate | ||||
| PSPTOA0037 | shikimate/metabolite | ||||
| PSPTOB0010 | hexuronate | ||||
| PSPTOB0043 | shikimate/metabolite | ||||
| The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily | |||||
| PROTEIN | SUBTYPE | POSSIBLE SUBSTRATE | TC# | ||
| PSPTO0370 12 | MATE | DinF homolog | |||
| PSPTO0115 12 | MATE | multidrug efflux | |||
| PSPTO4844 (dinF) 10 | MATE | DinF homolog | |||
| PSPTO3440 14 | PST | O-antigen | |||
| PSPTO3172 12 | MATE | DinF homolog | |||
| PSPTO2428 12 | MATE | multidrug efflux | |||
| The Malonate:Na+ Symporter (MSS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5079 (madM) 8 | malonate | ||||
| PSPTO5080 (madL) 4 | malonate | ||||
| The Nucleobase:Cation Symporter-1 (NCS1) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4975 12 | cytosine | ||||
| PSPTO1871 13 | cytosine/purines/uracil/thiamine/allantoin | ||||
| The Nucleobase:Cation Symporter-2 (NCS2) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4653 11 | xanthine/uracil | ||||
| PSPTO0772 12 | xanthine/uracil | ||||
| PSPTO1129 (uraA) 11 | uracil | ||||
| The NhaA Na+:H+ Antiporter (NhaA) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5174 (nhaA-2) 11 | sodium ion/proton | ||||
| PSPTO4533 (nhaA-1) 11 | sodium ion/proton | ||||
| The Metal Ion (Mn2+-iron) Transporter (Nramp) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5377 11 | sodium ion/proline | ||||
| PSPTO2464 11 | Mn2+/Fe2+ | ||||
| PSPTO2499 (mntH) 11 | manganese ion | ||||
| The Neurotransmitter:Sodium Symporter (NSS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4514 11 | sodium ion/? | ||||
| The Oligopeptide Transporter (OPT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0148 13 | oligopeptide | ||||
| The Cytochrome Oxidase Biogenesis (Oxa1) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5612 4 | 60 KD inner membrane protein YidC homolog | ||||
| The Inorganic Phosphate Transporter (PiT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4312 10 | phosphate | ||||
| PSPTO3702 9 | phosphate | ||||
| The Phosphate:Na+ Symporter (PNaS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0118 8 | sodium ion/phosphate | ||||
| The Resistance to Homoserine/Threonine (RhtB) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO2504 6 | amino acid efflux ? | ||||
| PSPTO0140 5 | homoserine/homoserine lactone efflux | ||||
| PSPTO3452 6 | amino acid efflux | ||||
| PSPTO2958 (rhtC) 4 | threonine | ||||
| PSPTO1147 5 | threonine | ||||
| PSPTO1885 6 | amino acid efflux | ||||
| PSPTO1221 6 | homoserine/homoserine lactone efflux | ||||
| The Resistance-Nodulation-Cell Division (RND) Superfamily | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO0375 12 | multidrug efflux | ||||
| PSPTO4304 11 | acriflavin/multidrug efflux | ||||
| PSPTO1517 ? 0 | multidrug efflux | ||||
| PSPTO1416 (secF) 6 PSPTO1415 (secD) 6 | protein export (SecDF) | ||||
| PSPTO1308 12 | multidrug efflux | ||||
| PSPTO2592 12 | acriflavin/multidrug efflux | ||||
| PSPTO2755 10 | acriflavin efflux | ||||
| PSPTO5191 11 | acriflavin efflux | ||||
| PSPTO3100 (mexF) 12 | multidrug efflux | ||||
| PSPTO3777 ? 12 | protein export? | ||||
| PSPTO0820 12 | acriflavin efflux | ||||
| PSPTO3302 11 | acriflavin efflux | ||||
| The Solute:Sodium Symporter (SSS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO1624 14 | sodium ion/solute | ||||
| PSPTO5016 12 | sodium ion/proline | ||||
| PSPTO3186 13 | sodium ion/proline | ||||
| The Sulfate Permease (SulP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4271 PSPTO4268 | sulfate | ||||
| PSPTO5256 10 | sulfate | ||||
| PSPTO3234 10 | sulfate | ||||
| PSPTO0168 11 | sulfate | ||||
| PSPTO3593 12 | sulfate | ||||
| The Twin Arginine Targeting (Tat) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO5155 (tatA) 0 PSPTO5156 (tatB) 0PSPTO5157 (tatC) 5 | protein export | ||||
| The Telurite-resistance/Dicarboxylate Transporter (TDT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO3541 10 | C4-dicarboxylate | ||||
| PSPTO4613 10 | C4-dicarboxylate/malic acid | ||||
| The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO1051 (dctP) 0 PSPTO1050 4PSPTO1049 (dctM) 11 | C4-dicarboxylate | ||||
| The K+ Transporter (Trk) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO1801 (trkH) 10 | potassium ion uptake | ||||
| The Tricarboxylate Transporter (TTT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| PSPTO4232 0 PSPTO4233 4PSPTO4234 12 | tricarboxylate | ||||
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