| Confidence Level of Functional Assignments: | |||||||||
 |
Weak Bioinformatic Evidence |  |
Strong Bioinformatic Evidence |  |
Clear Orthologue to Experimentally Characterized |  |
Experimental Characterized | ||
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| The Aspartate:Alanine Exchanger (AAE) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
DP0386  11 | aspartate/alanine? | ||||
| DP0976 11 | aspartate/alanine? | ||||
| The Arsenical Resistance-3 (ACR3) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1778 10 | arsenite | ||||
| The Auxin Efflux Carrier (AEC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1238 10 | malonate | ||||
| The Alanine or Glycine:Cation Symporter (AGCS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0706 11 | sodium ion/alanine | ||||
| DP1274 9 | sodium ion/alanine | ||||
| DP1275 9 | sodium ion/alanine | ||||
| DP1286 10 | sodium ion:D-alanine/glycine | ||||
| DP1296 11 | sodium ion:D-alanine/glycine | ||||
| The Amino Acid-Polyamine-Organocation (APC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0547 13 | amino acid | ||||
| DP0919 12 | amino acid | ||||
| DP2116 11 | amino acid | ||||
| DP2370 12 | amino acid | ||||
| The Arsenite-Antimonite (ArsB) Efflux Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP2070 11 | arsenite (ArsB) | ||||
| The Betaine/Carnitine/Choline Transporter (BCCT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0964 12 | glycine betaine/carnitine/choline | ||||
| DP1386 12 | glycine betaine | ||||
| DP1392 13 | glycine betaine | ||||
| DP1722 12 | choline | ||||
| The Ca2+:Cation Antiporter (CaCA) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0233 11 | proton/calcium ion | ||||
| The Cation Diffusion Facilitator (CDF) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0144 6 | cation efflux | ||||
| The Chloride Carrier/Channel (ClC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP3059 10 | chloride ion channel | ||||
| The Monovalent Cation:Proton Antiporter-1 (CPA1) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1228 12 | sodium ion/proton | ||||
| The Monovalent Cation:Proton Antiporter-2 (CPA2) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0306 10 | sodium ion/proton | ||||
| DP1776 12 | potassium ion efflux | ||||
| DP1913 10 | potassium ion efflux | ||||
| The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0138 9 | sodium ion/dicarboxylate | ||||
| DP1506 8 | proton/sodium ion:glutamate | ||||
| The Divalent Anion:Na+ Symporter (DASS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0767 13 | sodium ion/sulfate | ||||
| DP0768 3 | sodium ion/sulfate | ||||
| DP1441 11 | Sulfur-deprivation response protein homolog | ||||
| DP1490 13 | sodium ion/sulfate | ||||
| The C4-Dicarboxylate Uptake (Dcu) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0353 11 | C4-dicarboxylate | ||||
| DP2746 11 | C4-dicarboxylate | ||||
| The Drug/Metabolite Transporter (DMT) Superfamily | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0063 10 | drug/metabolite? | ||||
| DP0119 10 | drug/metabolite? | ||||
| DP0139 10 | drug/metabolite? | ||||
| DP0198 10 | drug/metabolite? | ||||
| DP0290 10 | drug/metabolite? | ||||
| DP0552 10 | drug/metabolite? | ||||
| DP0671 10 | drug/metabolite? | ||||
| DP1249 10 | drug/metabolite? | ||||
| DP1338 10 | drug/metabolite? | ||||
| DP1346 10 | chloramphenicol (RarD homolog) | ||||
| DP1347 10 | chloramphenicol (RarD homolog) | ||||
| DP1433 12 | drug/metabolite? | ||||
| DP1727 10 | drug/metabolite? | ||||
| DP1728 10 | drug/metabolite? | ||||
| DP1818 ? 10 | drug/metabolite? | ||||
| DP2196 10 | drug/metabolite? | ||||
| The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0956 11 | tyrosine | ||||
| DP1361 6 | tyrosine | ||||
| DP1362 5 | tyrosine | ||||
| The Lactate Permease (LctP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1023 14 | L-lactate | ||||
| DP2077 14 | L-lactate | ||||
| The Branched Chain Amino Acid Exporter (LIV-E) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP2465 5 | branched-chain amino acid efflux (AzlC) | ||||
| The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1397 12 | branched-chain amino acid | ||||
| The L-Lysine Exporter (LysE) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1687 6 | lysine efflux | ||||
| The Major Facilitator Superfamily (MFS) | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0155 13 | multidrug efflux | ||||
| DP0564 10 | drug efflux? | ||||
| DP1054 7 | fosmidomycin efflux | ||||
| DP1499 12 | glycerol-3-phosphate | ||||
| DP1861 14 | multidrug efflux | ||||
| DP1863 14 | multidrug efflux | ||||
| DP2323 12 | amino acid/amine? | ||||
| DP2747 11 | ? | ||||
| DP2838 12 | multidrug efflux | ||||
| DP2927 14 | AmpG homolog | ||||
| The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily | |||||
| PROTEIN | SUBTYPE | POSSIBLE SUBSTRATE | TC# | ||
| DP0039 14 | PST | O-antigen | |||
| DP0196 11 | MATE | multidrug efflux | |||
| DP1294 11 | MATE | multidrug efflux | |||
| DP2399 12 | MVF | virulence factor MviN homolog | |||
| The Nucleobase:Cation Symporter-2 (NCS2) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0673 7 | uracil | ||||
| DP0674 3 | uracil | ||||
| DP1412 12 | xanthine | ||||
| DP1495 12 | xanthine/uracil | ||||
| The NhaA Na+:H+ Antiporter (NhaA) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0669 11 | sodium ion/proton | ||||
| The NhaC Na+:H+ Antiporter (NhaC) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0097 12 | sodium ion/proton | ||||
| DP1702 12 | sodium ion/proton | ||||
| The NhaD Na+:H+ Antiporter (NhaD) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0848 14 | sodium ion/proton | ||||
| DP2085 5 | sodium ion/proton | ||||
| DP2086 7 | sodium ion/proton | ||||
| The Metal Ion (Mn2+-iron) Transporter (Nramp) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP2260 11 | manganese ion | ||||
| The Neurotransmitter:Sodium Symporter (NSS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0827 11 | sodium ion/? | ||||
| The Cytochrome Oxidase Biogenesis (Oxa1) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0855 5 | 60 KD inner membrane protein OxaA homolog | ||||
| The Inorganic Phosphate Transporter (PiT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP2628 10 | phosphate | ||||
| The Resistance to Homoserine/Threonine (RhtB) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0086 7 | homoserine/threonine efflux | ||||
| DP0509 6 | amino acid efflux | ||||
| DP1032 6 | threonine efflux | ||||
| DP1052 4 | amino acid efflux | ||||
| DP1261 6 | amino acid efflux | ||||
| DP2294 5 | amino acid efflux | ||||
| The Resistance-Nodulation-Cell Division (RND) Superfamily | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0371 12 | cation efflux | ||||
| DP0806 12 | protein-export (SecDF) | ||||
| DP1697 11 | acriflavine efflux | ||||
| DP2122 11 | acriflavine efflux | ||||
| DP2837 12 | multidrug efflux | ||||
| The Solute:Sodium Symporter (SSS) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0460 13 | sodium ion/pantothenate | ||||
| DP0691 13 | sodium ion/pantothenate | ||||
| The Sulfate Permease (SulP) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0163 12 | sulfate | ||||
| DP0288 11 | sulfate | ||||
| DP0849 11 | sulfate | ||||
| DP0931 10 | sulfate | ||||
| DP0967 12 | sulfate | ||||
| The Twin Arginine Targeting (Tat) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP1478 (tatC) 6 DP1479 (tatB)? 1DP1763 (tatC) 6 | protein export | ||||
| DP2620 (tatE) 1 DP2621 (tatA) 1DP2718 (tatC) 5 | protein export | ||||
| The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0357 0 DP0444 1DP0446 11 | C4-dicarboxylate | ||||
| DP0483 1 DP0484 11 | C4-dicarboxylate | ||||
| DP0486 1 DP0487 12DP0493 1 | C4-dicarboxylate | ||||
| DP0595 11 DP0596 4DP0597 1 | C4-dicarboxylate | ||||
| DP0744 19 DP0745 2 | ? | ||||
| DP1187 13 DP1188 4DP1189 1 | C4-dicarboxylate | ||||
| DP1357 11 DP1359 0 | ? | ||||
| DP1510 1 DP1511 4DP1512 11 | C4-dicarboxylate | ||||
| DP3053 17 DP3054 0DP3055 0 | C4-dicarboxylate | ||||
| The K+ Transporter (Trk) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0723 12 | potassium ion uptake | ||||
| DP0973 20 | potassium ion uptake | ||||
| The Tricarboxylate Transporter (TTT) Family | |||||
| PROTEIN | POSSIBLE SUBSTRATE | TC# | |||
| DP0535 12 DP0536 4DP0537 0 | tricarboxylate (TctABC) | ||||
| DP2243 1 DP2244 13 | tricarboxylate (TctCA) | ||||
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